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Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth f 1. Nat Genet. 2014 Oct 26. doi: 10.1038/ng.3122. [Epub ahead of print] Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS,
Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth f Centrioles are essential for ciliogenesis. However, mutations in centriole biogenesis genes have been reported in primary microcephaly and Seckel syndrome, disorders without the hallmark clinical features of ciliopathies. Here we identify mutations in the
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PCM Encoding and Decoding - Electrical, Computer & Biomedical Engineering • CLK: this is a TTL (red) input, and serves as the MASTER CLOCK for the module. Clock rate must be 10 kHz or less. For this experiment you will use the 8.333 kHz TTL signal from the MASTER SIGNALS module. The TIMS PCM time frame: Each binary word is ...
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Data Encoding Techniques, manchester encoding, 8b/10b The data bit '0' from the level-encoded signal is represented by a full normal cycle of the master clock which gives the '1' to '0' fall of the phase-encoded signal. i.e. +V in the first half of the signal and -V in the second ...
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